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KMID : 0363220150530080631
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Korean Journal of Dermatology
2015 Volume.53 No. 8 p.631 ~ p.634
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A Case of Autoimmune Progesterone Dermatitis Presenting as Erythema Multiforme
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Sung Nam-Hee
Kim Tae-Han
Kim Do-Hun
Shin Hyo-Seung
Lee Ai-Young
Lee Seung-Ho
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Abstract
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Autoimmune progesterone dermatitis is a rare disorder involving hypersensitivity to progesterone. It is most frequently characterized by recurrent erythema multiforme, eczematous or urticarial eruptions during the luteal phase of the menstrual cycle. It resolves or partially improves after menstruation. Sensitivity is demonstrated by a challenge test with medroxyprogesterone acetate. The therapeutic goal for autoimmune progesterone dermatitis is the suppression of ovulation. Currently, the first-line choice of therapy is a combination oral contraceptive. Here, we report a case of autoimmune progesterone dermatitis that manifested as cyclic bullous erythema multiforme. A reactive intradermal progesterone test confirmed the diagnosis.
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KEYWORD
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Autoimmune progesterone dermatitis, Erythema multiforme
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